In Crohn's disease, which symptom would prompt escalation of therapy?

In Crohn's disease, which symptom would prompt escalation of therapy?

• A. Persistent fever and abdominal pain despite treatment
• B. Weight gain and improved appetite
• C. No symptoms at all
• D. Decreased stool frequency

Answer: (C)

In Crohn's disease, signs that the disease remains active and not adequately controlled signal that therapy should be escalated. Persistent fever and abdominal pain despite treatment indicate ongoing inflammation or possible complications, so the treatment plan should be intensified or adjusted—this might mean optimizing current meds, adding a biologic agent, or reevaluating for infection or other issues requiring a different approach. Weight gain and improved appetite, no symptoms at all, and decreased stool frequency are all signs that the disease is under better control or in remission, so they do not prompt escalation. These outcomes suggest the current therapy is effective rather than needing to be strengthened.

In Crohn's disease, signs that the disease remains active and not adequately controlled signal that therapy should be escalated. Persistent fever and abdominal pain despite treatment indicate ongoing inflammation or possible complications, so the treatment plan should be intensified or adjusted—this might mean optimizing current meds, adding a biologic agent, or reevaluating for infection or other issues requiring a different approach.

Weight gain and improved appetite, no symptoms at all, and decreased stool frequency are all signs that the disease is under better control or in remission, so they do not prompt escalation. These outcomes suggest the current therapy is effective rather than needing to be strengthened.